Superfoods have been all the rage for the last few decades.  Although there is no standardized definition, this article out of UC Davis gives a great overview of how the term came to be–spoiler alert: it all started with bananas!  In simple terms, superfoods give you the best bang for your buck with their abundance of micronutrients (vitamins, minerals, antioxidants, and other important molecules that impart benefits at minimal quantity) without an overabundance of calories.  Think ancient grains, fruits, vegetables, and some fish. 

Since really digging into ingredients across all categories at the start of this year, I’ve noticed a plethora of fruit based ingredients, extracts and powders galore from widely recognized fruits as well as some that aren’t as well-known.  Fruit powders and ingredients highly interest me from a product development perspective because they can be used to add color and flavor beyond their micronutrient power.  Below is a small glimpse into a few ingredients I consider “superfruits” and am interested in for some current work projects:

  • Blood Orange and Oranges:  Oranges have always been known as a good source of vitamin C, yet only in recent years have scientists looked at the antioxidants within oranges and their potential health benefits.  New studies show that orange extracts may be helpful with anxiety and weight loss.  Orange components also show anticancer and cardioprotective activities.
  • Golden Kiwi:  To be honest, I had no idea gold kiwis were a thing until I had an ingredient supplier telling me about their golden kiwi powder.  I’ve learned that golden kiwis look just like their green counterparts with some differences in micronutrient content (e.g. gold kiwi has greater vitamin C and folate content than green kiwi).  Golden kiwi ingredients that I’ve seen thus far seem to primarily come from New Zealand, although kiwi can grow in several places around the globe.  Ingredients from golden kiwi can support digestive health and studies on kiwi show it contributes to an increase in high-density lipoprotein (HDL, aka the good cholesterol).
  • Pomegranate:  Yes, I’ve mentioned pomegranates previously in my recent liver ingredients post–I’ve been fascinated with pomegranates ever since learning about them in my high school mythology class (thank you, Mrs. Swartz!).   Pomegranate fits the superfruit mold because of all of the antioxidants it contains, like the anthocyanins that give pomegranate its red color.  The active components in pomegranate exhibit anticancer and anti-inflammatory activities, making it potentially useful in the treatment of cancers and arthritis.
  • Blueberries:  Like pomegranates, blueberries also contain anthocyanins.  In addition to the antioxidant potential of blueberries, recent research has shown they may be useful in slowing cognitive decline in older adults.
  • Kakadu Plum:  This fruit is another one whose existence I didn’t know until learning about it during a supplier meeting.  Kakadu plums are better known in Australia, and like the other superfruits listed here, have high antioxidant activity and micronutrient content.  Active components in Kakadu plums may be useful in inhibiting foodborne bacteria, thus potentially providing a natural alternative to some preservatives.  I had trouble locating any clinical research on ingredients from this interesting plant but it seems to have a long history of use in aboriginal medicine.

As research continues on plants, especially those used in traditional medicine around the world, I’m sure this list will continue to grow.  Are there specific fruits and fruit ingredients you find interesting for product development?  Are there any fruits you swear by in your diet?  I’d love to hear your thoughts, no matter how fruity.

October is Liver Cancer Awareness Month.  Since I’m married to a renowned hepatologist and gastroenterologist, I want to spend some time delving into ingredients that help us take care of the liver, the metabolic powerhouse of our bodies.  When I first started dating my husband, I thought the heart was the most important organ in the body.  He quickly proved me wrong.  Advances in science have allowed us to build mechanical hearts (or even grow a new heart from our own stem cells), but we cannot build a machine that can mimic the many metabolic functions the liver conducts for us every single day.  It’s truly a remarkable organ.  Did you know that after a live donor liver transplant, the liver will regenerate in both the donor and the recipient in about three months?  You learn a lot of interesting things with a liver doc in the house.

Ingredients FOR LIVER HEALTH

So where does liver health intersect with food science?  Over the last decade, scientists have begun to study the hepatoprotective effect of certain ingredients.  I briefly touched on this in a Prepared Foods article last year when I shared aged black garlic was shown to have hepatoprotective benefit in a pre-clinical trial.  Beyond this, there are several other ingredient options that may be helpful in improving liver health and function.  Below are a few I find interesting:

  • Pomegranate Extract:  The fruit of the gods gets a lot of great press for its antioxidant content and delightfully tart flavor.  demonstrated the hepatoprotective effect of a phenolic-rich pomegranate extract in mice fed a high fat diet.  A similar report in Frontiers in Pharmacology published last year showed pomegranate also had hepatoprotective activity against liver damage induced by CCl4 in rats.  Pomegranate-based ingredients are perfect for providing natural color and flavor–understanding their health impact make them a great multi-faceted choice for food and supplement formulations.
  • Soy and Whey Proteins:  Proteins are a deep area of fascination for me because of the wide varieties of functionality whole proteins and their hydrolysates provide to food, not to mention their inherent nutritional value.  Thus I found it highly intriguing that soy consumption was associated with reduced incidence of non-alcoholic fatty liver disease (NAFLD) according to a recent study in the Journal of Nutrition.  Perhaps this is due to one soy protein in particular, β-conglycinin, as a 2018 review article in the International Journal of Molecular Sciences highlighted the hepatoprotective effects of β-conglycinin against NAFLD as well as alcohol induced fatty liver disease.  Additionally, a study published last year in Nutrients showed the hepatoprotective effects in pre-clinical work of a foam made with whey protein hydrolysate and stabilized by a polysaccharide combination.  The same foam also showed anti-hypertensive activity, which I don’t find the least bit surprising as dairy proteins are known for being an excellent source of bioactive peptides.  Proteins could be as good for the liver as they are for the diet.
  • Trehalose:  A naturally occurring sugar found in many foodstuff, trehalose often is used in food formulations because of its ability to retain moisture and reduce freezing points.  Several studies published in the last five years have linked trehalose with a weakening of liver disease in pre-clinical trials. 

There are several other botanical actives and ingredients being studied for their impact on liver function, but I chose to highlight the above, as it is helpful for formulators when a single ingredient provides multiple benefits.  I should note that curcumin, the active component of turmeric, also is of great interest for treating NAFLD.  However, with the plethora of curcumin ingredients currently on the market and most of them claiming to be the most bioavailable form, I want to investigate further and address the topic in a future post. 

LOVE YOUR LIVER BY LOVING YOUR GUT

It’s also worth noting that researchers have taken note of the existence of the gut-liver axis, by which our gut microbiome plays a role in liver health and vice versa.  When the gut microbiome isn’t well maintained, it can play a role in liver disease, but by taking care of our gut, we can positively impact liver health.  A review article published in the International Journal of Molecular Sciences in 2016 highlighted probiotics may be helpful in the treatment of NAFLD, among other issues such as obesity and type 2 diabetes.  It’s a common theme you will often hear from me–our gut plays an important role in many bodily functions.  So if you want to love your liver, make sure you love your gut too!

If you are interested in learning more about ingredients for liver health, leave me a comment below or connect with me on Twitter.